Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Vindesine sulfate European Pharmacopoeia (EP) Reference Standard | 59917-39-4 | MFCD01636152 |
Vindesine sulfate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 852 | 59917-39-4 | MFCD01636152 |
Sigma Aldrich Fine Chemicals Biosciences Mexiletine impurity D European Pharmacopoeia (EP) Reference Standard | 26583-71-1 |
Mexiletine impurity D European Pharmacopoeia (EP) Reference Standard | Mol Wt: 179.26 | 26583-71-1 |
Apexbio Technology LLC Cabozantinib (XL184, BMS-907351) 849217-68-1 10mM (in 1mL DMSO)
Cabozantinib (XL184 BMS-907351 CAS 849217-68-1) is a small molecule inhibitor targeting multiple receptor tyrosine kinases (RTKs) notably VEGFR2 MET and RET with reported IC50 values of 0 035 nmol/L 1 3 nmol/L and 5 2 nmol/L respectively Acting by blocking downstream phosphorylation events cabozantinib disrupts RTK-mediated cell signaling pathways fundamental to cellular proliferation and differentiation In vitro studies utilizing RET-mutant TT cells showed dose-dependent inhibition of RET autophosphorylation (IC50 85 nmol/L) and reduced cellular proliferation In vivo experiments using TT-cell xenograft mouse models demonstrated tumor growth suppression and decreased serum calcitonin levels Cabozantinib serves as a valuable tool in oncology and RTK-related signaling research
Apexbio Technology LLC Cabazitaxel 183133-96-2 5mg
Cabazitaxel (CAS 183133-96-2) is a semisynthetic compound derived from the natural precursor 10-deacetylbaccatin III belonging to the taxoid class of antineoplastic agents It exerts its biological effects primarily by stabilizing microtubules thus disrupting mitotic and interphase cellular functions and causing cell-cycle arrest leading to apoptosis Due to this microtubule-targeting activity cabazitaxel is extensively studied in oncology research particularly investigating chemoresistant tumor cell lines and therapeutic approaches for taxane-resistant cancers
Medchemexpress LLC 5H-1-Benzazepin-5-one, 1-(4-amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro- | 137977-97-0 | 99.9% | 328.80 | 500 MG
Tolvaptan Impurity from MedChemExpress is a chemical compound with the molecular formula C18H17ClN2O2 and a molecular weight of 328.80. It is provided as a white to off-white solid with a purity of 99.92%. This product is intended for research use only and has not been fully validated for medical applications.
- Provided as a white to off-white solid
- Purity of 99.92%
- Suitable for research applications
- Store as powder at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
Selleck Chemical LLC Cefditoren Pivoxil 10mg 117467-28-4 ME-1207
Cefditoren Pivoxil (ME-1207) is a broad-spectrum antibiotic against Gram-negative and Gram-positive bacteria. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Fenofibrate Related Compound B United States Pharmacopeia (USP) Reference Standard | 42017-89-0 | MFCD00792461 | 25MG
Fenofibrate Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 318.75 | 42017-89-0 | MFCD00792461 | 25MG
Apexbio Technology LLC Glycopyrrolate 596-51-0 25mg
Glycopyrrolate (CAS 596-51-0) is a small molecule that acts as a competitive antagonist of muscarinic acetylcholine receptors By blocking muscarinic receptor-mediated cholinergic signaling it inhibits smooth muscle contractions and reduces secretory gland activity This pharmacological profile makes glycopyrrolate a valuable tool in studies investigating muscarinic receptor function neurotransmission and cholinergic pathways It is frequently used in research focused on gastrointestinal motility airway regulation and autonomic nervous system modulation
Apexbio Technology LLC Fostamatinib (R788) 901119-35-5 10mg
Fostamatinib (R788 CAS 901119-35-5) is an orally available small-molecule inhibitor targeting spleen tyrosine kinase (Syk) with an IC50 of approximately 41 nM As a prodrug fostamatinib is rapidly converted to its active metabolite R406 an ATP-competitive inhibitor of Syk (Ki 30 nM) R406 additionally inhibits related kinases such as Flt3 Lyn (IC50 63 nM) and Lck (IC50 37 nM) thereby modulating BCR- and Fc receptor-mediated signaling pathways Preclinical studies demonstrate activity of fostamatinib in various autoimmune and inflammatory models including SLE-related nephritis and dermatitis in MRL/lpr mice highlighting its utility as a research tool in autoimmune disease investigation
Medchemexpress LLC Impurity C of calcitriol | 86307-44-0 | MFCD22124487 | 99.8% | C35H49N3O5 | 10MG
Impurity C of calcitriol (CAS 86307-44-0) is a characterized impurity of calcitriol used as an analytical reference standard in research and method development. Supplied as a high-purity solid, it is intended for chromatographic and spectroscopic applications; users should consult the lot-specific certificate of analysis for exact specifications.
- High purity suitable for analytical standards and reference use.
- Provided as a solid for convenient handling and storage.
- Compatible with chromatographic and spectroscopic methods.
- Useful for impurity profiling and method validation.
- Batch-specific certificate of analysis available for exact specifications.
Medchemexpress LLC Ganoderic acid A | 81907-62-2 | 516.67 | 1 ML
Ganoderic acid A can inhibit the JAK-STAT3 signaling pathway, and also inhibit proliferation, viability, and ROS. This compound is intended for research use only and not for sale to patients.
- Inhibits JAK-STAT3 signaling pathway
- Inhibits proliferation, viability, and ROS
- Cytotoxic against Bel-7402 cells with an IC50 of 7.25 μM
- Cytotoxic against HepG2 cells with a CC50 of 80 μM and IC50 of 38.7 μM
- Enhances HLA class II-mediated antigen presentation
- Promotes cisplatin-induced cell death via STAT3 suppression
- Inhibits proliferation and induces apoptosis in human osteosarcoma HOS and MG-63 cells
- High purity of 99.26%
- Soluble in DMSO and ethanol
- Shipped at room temperature
- Storage at 4°C (solid) and -80°C/-20°C (in solvent)
U.S. Pharmacopeia Hydrocortisone Hemisuccinate, 83784-20-7, 200mg
Molecular formula C25H34O8, Molecular weight 480.55, Melting Point 419 °F (215 °C), Synonyms: Hydrocortisone hydrogen succinate
Cayman Chemical 4hydroxy Diclofenac
An active metabolite of diclofenac; inhibits COX activity (IC50 = 32 nM) and reduces PGE2 production (IC50 = 17 nM) in isolated human rheumatoid synovial cells
Sigma Aldrich Fine Chemicals Biosciences Bufexamac impurity D European Pharmacopoeia (EP) Reference Standard | 3413-59-0 |
Bufexamac impurity D European Pharmacopoeia (EP) Reference Standard | Mol Wt: 207.27 | 3413-59-0 |
Medchemexpress LLC D-(4-hydroxyphenyl)glycylamoxicillin | 188112-75-6 | MFCD27967048 | 100mg
Amoxicillin Impurity 5 is an impurity of Amoxicillin (HY-B0467A)